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Dykhuizen Lab

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Amazing collaborator papers!

1/30/2019

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Several manuscripts we collaborated on are published! 

The Musselman Lab
They published a nice manuscript characterizing the SANT1 domain of EZH2 using NMR. They find that it recognizes the the histone H4 N-terminal tail and that this binding is antagonized by various activating marks. "The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail."
https://www.ncbi.nlm.nih.gov/pubmed/30700785

The Weake Lab
They characterized a cool new chiffon histone acetyltransferase (CHAT) complex unique to flies in: "The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability."
https://www.ncbi.nlm.nih.gov/pubmed/30559249

Thanks for including us in your awesome science!
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